Abstract The cannabidiol (CBD)-rich cannabis extract CAN296 shows anti-inflammatory and anticancer activity relevant to oral lichen planus (OLP), oral graft-versus-host…
Abstract This study investigates the immunomodulatory effects of a well-characterized cannabidiol (CBD)-rich cannabis extract, CAN296, on T lymphocytes (T cells),…
Abstract Background: The efficacy of medical cannabis in alleviating pain has been demonstrated in clinical trials, yet questions remain regarding…
Abstract In T-cell acute lymphoblastic leukemia (T-ALL), more than 50% of cases display autoactivation of Notch1 signaling, leading to oncogenic…
Abstract Introduction: As the medical use of Cannabis is evolving there is a greater demand for high-quality products for patients.…
Abstract The prevalence of obesity and obesity-related pathologies is lower in frequent cannabis users compared to non-users. It is well…
Abstract We aimed to elucidate the effect of Medical Cannabis (MC) on appetite and nutritional status among patients with inflammatory…
Abstract Background: Clinical studies on medical cannabis (MC) treatment have shown sex-related differences, including higher susceptibility to adverse events among…
Abstract Prolonged cannabis users show a lower prevalence of obesity and associated comorbidities. In rodent models, Δ9-tetrahydrocannabinol (THC) and cannabidiol…
Abstract During solid tumor progression, the tumor microenvironment (TME) evolves into a highly immunosuppressive milieu. Key players in the immunosuppressive…