Proteomic Profile of Circulating Extracellular Vesicles in the Brain after Δ9-Tetrahydrocannabinol Inhalation
Abstract Given the increasing use of cannabis in the US, there is an urgent need to better understand the drug’s…
Daniele Piomelli
A preclinical model of THC edibles that produces high-dose cannabimimetic responses
Abstract No preclinical experimental approach enables the study of voluntary oral consumption of high-concentration Δ9-tetrahydrocannabinol (THC) and its intoxicating effects,…
Persistent sexually dimorphic effects of adolescent THC exposure on hippocampal synaptic plasticity and episodic memory in rodents
Abstract There is evidence that cannabis use during adolescence leads to memory and cognitive problems in young adulthood but little…
Fast and Sensitive Quantification of Δ9-Tetrahydrocannabinol and Its Main Oxidative Metabolites by Liquid Chromatography/Tandem Mass Spectrometry
Abstract Introduction: Few animal studies have evaluated the pharmacological effects of Δ9-tetrahydrocannabinol (THC) in relation to its pharmacokinetic properties. Understanding…
Cannabis and the Opioid Crisis
Authors: Daniele Piomelli, Susan Weiss, Graham Boyd, Rosalie Liccardo Pacula, Ziva Cooper Affiliations: Department of Anatomy and Neurobiology School of…
Medicinal Cannabis in California: An Interview with Igor Grant, MD
Abstract Dr. Igor Grant, MD, is distinguished professor and chair of psychiatry and director of the HIV Neurobehavioral Research Program…
The Cannabis sativa Versus Cannabis indica Debate: An Interview with Ethan Russo, MD
Abstract Dr. Ethan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and Medical Director of PHYTECS, a biotechnology company researching…
Seventh European Workshop on Cannabinoid Research and IACM Eighth Conference on Cannabinoids in Medicine
Abstract The joint 7th European Workshop on Cannabinoid Research and IACM 8th Conference on Cannabinoids in Medicine was held in…
Legal or Illegal, Cannabis Is Still Addictive
Authors: Daniele Piomelli, Margaret Haney, Alan J. Budney, Pier Vincenzo Piazza Affiliations: Department of Anatomy and Neurobiology, School of Medicine,…
Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition
Abstract Evidence shows that the endocannabinoid system modulates the addictive properties of nicotine. In the present study, we hypothesized that…