Multi-omics analysis of the oncogenic role of optic atrophy 1 in human cancer
Abstract Objective: To investigate the prognostic significance of optic atrophy 1 (OPA1) in pan-cancer and analyze the relationship between OPA1…
Daiwen Yang
Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity
Abstract Specificity of RNA-binding proteins for target sequences varies considerably. Yet, it is not understood how certain few proteins achieve…
GPX3 expression was down-regulated but positively correlated with poor outcome in human cancers
Abstract Introduction: Cancer is a crucial public health problem and one of the leading causes of death worldwide. Previous studies…
Structural Basis of Oligomerization of N-Terminal Domain of Spider Aciniform Silk Protein
Abstract Spider silk is self-assembled from water-soluble silk proteins through changes in the environment, including pH, salt concentrations, and shear…
Construction of prognostic microRNA signature for human invasive breast cancer by integrated analysis
Abstract Background: Despite the advances in early detection and treatment methods, breast cancer still has a high mortality rate, even…