Functional Adaptation in the Brain Habenulo–Mesencephalic Pathway During Cannabinoid Withdrawal
Abstract The mesolimbic reward system originating from dopamine neurons in the ventral tegmental area (VTA) of the midbrain shows a…
Claudia Sagheddu
Presynaptic nanoscale components of retrograde synaptic signaling
Abstract While our understanding of the nanoscale architecture of anterograde synaptic transmission is rapidly expanding, the qualitative and quantitative molecular…
Repeated exposure to JWH‐018 induces adaptive changes in the mesolimbic and mesocortical dopaminergic pathways, glial cells alterations, and behavioural correlates
Abstract Background and Purpose: Spice/K2 herbal mixtures, containing synthetic cannabinoids such as JWH‐018, have been marketed as marijuana surrogates since…
Prenatal THC Does Not Affect Female Mesolimbic Dopaminergic System in Preadolescent Rats
Abstract Cannabis use among pregnant women is increasing worldwide along with permissive sociocultural attitudes toward it. Prenatal cannabis exposure (PCE),…
Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone
Abstract Increased legal availability of cannabis has led to a common misconception that it is a safe natural remedy for,…
Cell-specific STORM superresolution imaging reveals nanoscale organization of cannabinoid signaling
Abstract A major challenge in neuroscience is to determine the nanoscale position and quantity of signaling molecules in a cell-type-,…