Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region
Abstract The three human pathogenic ebolaviruses: Zaire (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) virus, cause severe disease with high fatality…
Clara T. Schoeder
Computational Investigations on the Binding Mode of Ligands for the Cannabinoid-Activated G Protein-Coupled Receptor GPR18
Abstract GPR18 is an orphan G protein-coupled receptor (GPCR) expressed in cells of the immune system. It is activated by…
Pharmacological evaluation of new constituents of “Spice”: synthetic cannabinoids based on indole, indazole, benzimidazole and carbazole scaffolds
Abstract Purpose: In the present study we characterized a series of synthetic cannabinoids containing various heterocyclic scaffolds that had been…
Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice
Abstract Electronic supplementary material: The online version of this article (doi:10.1007/s11419-016-0320-2) contains supplementary material, which is available to authorized users.…