Longitudinal study of risk factors predicting cannabis use disorder in UK young adults and adolescents
Abstract Background: Cannabis use disorder (CUD) affects up to 1 in 5 people who try cannabis. In order to develop…
Claire Mokrysz
Acute effects of different types of cannabis on young adult and adolescent resting-state brain networks
Abstract Adolescence is a time of rapid neurodevelopment and the endocannabinoid system is particularly prone to change during this time.…
Persistent increased severity of cannabis use disorder symptoms in adolescents compared to adults: a one-year longitudinal study
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00406-024-01806-y. Article type: Research Article Keywords: Cannabis use disorder,…
The acute effects of cannabis, with and without cannabidiol, on attentional bias to cannabis related cues: a randomised, double-blind, placebo-controlled, cross-over study
Abstract Rationale: Attentional bias to drug-related stimuli is hypothesised to contribute towards addiction. However, the acute effects of Δ9-tetrahydrocannabinol (THC)…
The acute effects of cannabis with and without cannabidiol in adults and adolescents: A randomised, double‐blind, placebo‐controlled, crossover experiment
Abstract Background and Aims: Long‐term harms of cannabis may be exacerbated in adolescence, but little is known about the acute…
The CannTeen Study: Cannabis use disorder, depression, anxiety, and psychotic-like symptoms in adolescent and adult cannabis users and age-matched controls
Abstract Background: Adolescence is characterised by psychological and neural development. Cannabis harms may be accentuated during adolescence. We hypothesised that…
Individual and combined effects of cannabidiol and Δ9-tetrahydrocannabinol on striato-cortical connectivity in the human brain
Abstract Background: Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the two major constituents of cannabis with contrasting mechanisms of action. THC…
The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use
Abstract Background: The lack of an agreed international minimum approach to measuring cannabis use hinders the integration of multidisciplinary evidence…
Cannabis Dampens the Effects of Music in Brain Regions Sensitive to Reward and Emotion
Abstract Background: Despite the current shift towards permissive cannabis policies, few studies have investigated the pleasurable effects users seek. Here,…
Acute and chronic effects of cannabinoids on effort-related decision-making and reward learning: an evaluation of the cannabis ‘amotivational’ hypotheses
Abstract Rationale: Anecdotally, both acute and chronic cannabis use have been associated with apathy, amotivation, and other reward processing deficits.…