Christopher I. Amos

January 19, 2022

Whole-chromosome arm acquired uniparental disomy in cancer development is a consequence of isochromosome formation

Abstract Using SNP-based microarray data from The Cancer Genome Atlas (TCGA), we investigated isochromosomes (deletion of one arm and duplication…

September 25, 2021

Pan-cancer evaluation of gene expression and somatic alteration data for cancer prognosis prediction

Abstract Background: Over the past decades, approaches for diagnosing and treating cancer have seen significant improvement. However, the variability of…

October 20, 2020

Cancer prognosis prediction using somatic point mutation and copy number variation data: a comparison of gene-level and pathway-based models

Abstract Background: Genomic profiling of solid human tumors by projects such as The Cancer Genome Atlas (TCGA) has provided important…