A pan-cancer analysis of the oncogenic and immunological roles of transglutaminase 1 (TGM1) in human cancer
Abstract Background: There is currently a limited number of studies on transglutaminase type 1 (TGM1) in tumors. The objective of…
Chi Zhang
CBD2: A functional biomarker database for colorectal cancer
Abstract The rapidly evolving landscape of biomarkers for colorectal cancer (CRC) necessitates an integrative, updated repository. In response, we constructed…
Pan-cancer analysis identifies NT5E as a novel prognostic biomarker on cancer-associated fibroblasts associated with unique tumor microenvironment
Abstract Background: Ecto-5′-nucleotidase (NT5E) encodes the cluster of differentiation 73 (CD73), whose overexpression contributes to the formation of immunosuppressive tumor…
Pan-cancer analyses confirmed the cuproptosis-related gene FDX1 as an immunotherapy predictor and prognostic biomarker
Abstract Background: The latest research identified cuproptosis as an entirely new mechanism of cell death. However, as a key regulator…
Acid–base Homeostasis and Implications to the Phenotypic Behaviors of Cancer
Abstract Acid–base homeostasis is a fundamental property of living cells, and its persistent disruption in human cells can lead to…
Fenton reactions drive nucleotide and ATP syntheses in cancer
Abstract We present a computational study of tissue transcriptomic data of 14 cancer types to address: what may drive cancer…
Elective laparoscopic cholecystectomy without intraoperative cholangiography: role of preoperative magnetic resonance cholangiopancreatography – a retrospective cohort study
Abstract Background: Laparoscopic cholecystectomy (LC) is the standard treatment for gallbladder diseases. Intraoperative cholangiography (IOC) can reduce biliary complications of…