Cheryl H Arrowsmith

April 13, 2017

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage

Abstract Site-specific histone ubiquitylation plays a central role in orchestrating the response to DNA double-strand breaks (DSBs). DSBs elicit a…

December 4, 2014

A global assessment of cancer genomic alterations in epigenetic mechanisms

Abstract Background: The notion that epigenetic mechanisms may be central to cancer initiation and progression is supported by recent next-generation…