Prognostic Implication and Oncogenic Role of PNPO in Pan-Cancer
Abstract Objective: Pyridoxine 5′-phosphate oxidase (PNPO) is a key enzyme in the metabolism of vitamin B6 and affects the tumorigenesis…
Chengxin Li
Identifying and characterizing lincRNA genomic clusters reveals its cooperative functions in human cancer
Abstract Background: Emerging evidence has revealed that some long intergenic non-coding RNAs (lincRNAs) are likely to form clusters on the…
Analysis of the Prognostic Value and Potential Molecular Mechanisms of TREM-1 Overexpression in Papillary Thyroid Cancer via Bioinformatics Methods
Abstract Background: Triggering receptor expressed on myeloid cells-1 (TREM-1) has been reported as a biomarker in many cancers. However, the…
Analysis of the expression and potential molecular mechanism of interleukin-1 receptor antagonist (IL1RN) in papillary thyroid cancer via bioinformatics methods
Abstract Background: Interleukin-1 receptor antagonist (IL1RN) has been reported as a biomarker of many cancers. However, the biological function of…
Immune Cell Confrontation in the Papillary Thyroid Carcinoma Microenvironment
Abstract Background: Papillary thyroid cancer has been associated with chronic inflammation. A systematic understanding of immune cell infiltration in PTC…
Bioinformatics analysis of the clinical value and potential mechanisms of AHNAK2 in papillary thyroid carcinoma
Abstract Background: AHNAK2 has been recently reported as a biomarker in many cancers. However, a systematic investigation of AHNAK2 in…
Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
Abstract Store-operated calcium entry (SOCE) is a major pathway for calcium ions influx into cells and has a critical role…