NXPH4 can be used as a biomarker for pan-cancer and promotes colon cancer progression
Abstract NXPH4 promotes cancer proliferation and invasion. However, its specific role and mechanism in cancer remain unclear. Transcriptome and clinical…
Chao Zhang
Pan-cancer analysis of SYNGR2 with a focus on clinical implications and immune landscape in liver hepatocellular carcinoma
Abstract Background: Synaptogyrin-2 (SYNGR2), as a member of synaptogyrin gene family, is overexpressed in several types of cancer. However, the…
The prognostic and immunological role of MYB: from bladder cancer validation to pan-cancer analysis
Abstract Background: MYB proto-oncogene is verified as a transcription factor. Although emerging evidence showed that MYB plays a critical part…
Supplemental Clostridium butyricum modulates lipid metabolism by reshaping the gut microbiota composition and bile acid profile in IUGR suckling piglets
Abstract Background: Intrauterine growth restriction (IUGR) can cause lipid disorders in infants and have long-term adverse effects on their growth…
Identification of a Novel Cuproptosis-Related Gene Signature and Integrative Analyses in Thyroid Cancer
Abstract Cuproptosis is a novel programmed cell death that depends on copper. The role and potential mechanism of cuproptosis-related genes…
A pan-cancer and single-cell sequencing analysis of CD161, a promising onco-immunological biomarker in tumor microenvironment and immunotherapy
Abstract Background: CD161 has been linked to the appearance and development of various cancers. Methods: The mutation map and the…
Multi-omics pan-cancer study of cuproptosis core gene FDX1 and its role in kidney renal clear cell carcinoma
Abstract Background: The mechanism of copper-induced cellular death was newly discovered and termed cuproptosis. Inducing cuproptosis in cancer cells is…
Estimates of prevalence, time-trend, and association of smoking in adults living with HIV, HBV, and HCV (NHANES 1999–2018)
Abstract Although the smoking rate of human immunodeficiency virus (HIV), hepatitis B virus (HBV) or hepatitis C virus (HCV) infected…
Identification of CD73 as a Novel Biomarker Encompassing the Tumor Microenvironment, Prognosis, and Therapeutic Responses in Various Cancers
Abstract Simple Summary: Immunotherapy targeting immune checkpoints and stromal cells in the tumor microenvironment is currently one of the most…
Identify the immune characteristics and immunotherapy value of CD93 in the pan-cancer based on the public data sets
Abstract CD93 is a transmembrane receptor that is mainly expressed on endothelial cells. A recent study found that upregulated CD93…