Pan-cancer association of a mitochondrial function score with genomic alterations and clinical outcome
Abstract Mitochondria are pivotal in cellular energy metabolism and have garnered significant attention for their roles in cancer progression and…
Changyue Liu
Construction of thyroid cancer classification and iodine metabolism related diagnostic model using thyroid differentiation score and bioinformation
Abstract To more accurately diagnose and treat patients with different subtypes of thyroid cancer, we constructed a diagnostic model related…
CAPN8 involves with exhausted, inflamed, and desert immune microenvironment to influence the metastasis of thyroid cancer
Abstract Background: Thyroid cancer (THCA) is the most prevalent malignant disease of the endocrine system, in which 5-year survival can…
Explore the multitarget mechanism of tetrahydrocurcumin preventing on UV-induced photoaging mouse skin
Abstract UV induced photoaging is the main external factor of skin aging. In this study, we tested the protective effects…
Bioinformatics Analyses Reveal the Prognostic Value and Biological Roles of SEPHS2 in Various Cancers
Abstract Purpose: Selenophosphate synthetase 2 (SEPHS2) has been shown to regulate selenoprotein biosynthesis by catalyzing the synthesis of active selenium…
Inferring probabilistic miRNA–mRNA interaction signatures in cancers: a role-switch approach
Abstract Aberrant microRNA (miRNA) expression is implicated in tumorigenesis. The underlying mechanisms are unclear because the regulations of each miRNA…