Unveiling the multifaceted role of the FLNC gene: implications for cancer diagnosis and prognosis
Abstract Background: The Filamin C (FLNC) gene, pivotal for cellular structure and function, holds significance in cancer biology. Methods: We…
Changqian Wang
Prognostic and immunological role of RHEBL1 in pan-cancer: a target for survival and immunotherapy
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s12672-025-02544-w. Article type: Research Article Keywords: RHEBL1, Immune cell…
Comprehensive Pan-cancer Analysis Revealed CASP10 As a Promising Biomarker For Diverse Tumor Types
Abstract We aimed to explore the comprehensive cancer landscape of Caspase-10 (CASP10). CASP10, a member of the caspase family, is…
Pan-Cancer Analysis and Experimental Validation of SOX4 as a Potential Diagnosis, Prognosis, and Immunotherapy Biomarker
Abstract Simple Summary: Data show that the global cancer burden continues to grow. It is estimated that there were 19.3…
Association of dual electronic cigarettes and marijuana use with sleep duration among adults from the United States, NHANES 2015–2018
Abstract Electronic cigarette (e-cigarette) use is becoming more widespread, and studies show that they are not absolutely harmless. To investigate…
Comprehensive Analysis Reveals USP45 as a Novel Putative Oncogene in Pan-Cancer
Abstract Background: Deubiquitinating enzymes specifically removes ubiquitin molecules from ubiquitin-tagged target proteins, thereby inhibiting the degradation of target proteins and…
Integrative Pan-Cancer Analysis Confirmed that FCGR3A is a Candidate Biomarker Associated With Tumor Immunity
Abstract Background: Fc gamma receptor 3A (FCGR3A) encodes a receptor for the Fc portion of immunoglobulin G, which plays a…
A systematic analysis of immune genes and overall survival in cancer patients
Abstract Background: Overall survival (OS) is a key endpoint measure in the management of patients with cancer. Immunotherapy has become…
Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells
Abstract Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide. Reactive oxygen species (ROS), as…