Casey M. Theriot

May 1, 2023

Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis

Abstract Clostridioides difficile is the leading cause of hospital-acquired diarrhea worldwide. While TcdB, the primary virulence determinant of C. difficile,…

January 6, 2016

Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine

Abstract Antibiotics alter the gastrointestinal microbiota, allowing for Clostridium difficile infection, which is a significant public health problem. Changes in…