Abstract Background: Integrin Subunit Alpha 4 (ITGA4), a member of the integrin protein family, is involved in the progression of…
Abstract Background: Neuronal guanine nucleotide exchange factor (NGEF) plays a key role in several cancers; however, its role in lung…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s40001-024-01684-z. Article type: Research Article Keywords: MDM4, Pan-cancer, Prognostic…
Abstract Purpose: Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases. Immediate early response 5 like…
Abstract There is growing interest in non-psychoactive phytocannabinoids, namely cannabidiol (CBD), cannabigerol (CBG), and cannabichromene, as potential leads for novel…
Abstract Objective: To explore the possible mechanisms of cholestasis induced by Polygoni Multiflori Radix (PM). Methods: Low and high doses…
Abstract Objective: Large volume radiological text data have been accumulated since the incorporation of electronic health record (EHR) systems in…
Abstract Novel therapy strategies are crucial for thyroid carcinoma treatment. It is increasingly important to clarify the mechanism of thyroid…
Abstract Seven-transmembrane receptors signal via G-protein- and β-arrestin-dependent pathways. We describe a peripheral CB1R antagonist (MRI-1891) highly biased toward inhibiting…