KIF23 silencing suppresses papillary thyroid carcinoma metastasis by regulating mitophagy via Wnt/β-catenin pathway
Abstract Background: Kinesin family member 23 (KIF23) plays a critical role in the regulation of cell division. This study aims…
Bowen Chen
Development and external validation of the ‘Global Surgical-Site Infection’ (GloSSI) predictive model in adult patients undergoing gastrointestinal surgery
Abstract Background: Identification of patients at high risk of surgical-site infections may allow surgeons to minimize associated morbidity. However, there…
Taurohyocholic acid acts as a potential predictor of the efficacy of tyrosine kinase inhibitors combined with programmed cell death-1 inhibitors in hepatocellular carcinoma
Abstract Background and aims: Tyrosine kinase inhibitors (TKIs) combined with programmed cell death protein-1 (PD-1) have significantly improved survival in…
Model to assess workload of village doctors in the National Essential Public Health Services Program in six provinces of China
Abstract Background: No studies, particularly quantitative analyses, have been conducted regarding the workload of village doctors in the National Essential…
TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells
Abstract Recognition of specific chromatin modifications by distinct structural domains within “reader” proteins plays a critical role in the maintenance…