Lung microbiota: a new hope for treating acute respiratory distress syndrome?
Abstract The lung microbiota, present in healthy individuals, undergoes alterations in different diseases and is closely linked to changes in…
Bo Wang
The Impact of Major and Minor Phytocannabinoids on the Maintenance and Function of INS-1 β-Cells Under High-Glucose and High-Lipid Conditions
Abstract Type 2 diabetes mellites (T2DM) is the most common form of diabetes and affects a significant portion of the…
Anti-Inflammatory Effects of Minor Cannabinoids CBC, THCV, and CBN in Human Macrophages
Abstract Inflammation is a natural response of the body to signals of tissue damage or infection caused by pathogens. However,…
High-CBD cannabis extracts inhibit the expression of proinflammatory factors via miRNA-mediated silencing in human small intestinal epithelial cells
Abstract The incidence of chronic inflammatory disorders and autoimmune diseases is rapidly growing. To date, the COVID-19 pandemic caused by…
Use of Cannabis and Cannabinoids for Treatment of Cancer
Abstract Simple Summary: Cancer is a disease which affects approximately 40% of people in their lifetime. Chemotherapy, the primary choice…
Cannabinol Inhibits Cellular Proliferation, Invasion, and Angiogenesis of Neuroblastoma via Novel miR-34a/tRiMetF31/PFKFB3 Axis
Abstract Simple Summary: The prognosis of high-risk neuroblastoma is poor due to its high relapse rate. To date, no effective…
New AKT-dependent mechanisms of anti-COVID-19 action of high-CBD Cannabis sativa extracts
Abstract COVID-19 is caused by the SARS-CoV-2 virus, which enters target cells via interactions with ACE2 and TMPRSS2. Here, we…
Fighting the storm: could novel anti-TNFα and anti-IL-6 C. sativa cultivars tame cytokine storm in COVID-19?
Abstract The main aspects of severe COVID-19 disease pathogenesis include hyper-induction of proinflammatory cytokines, also known as ‘cytokine storm’, that…
In search of preventive strategies: novel high-CBD Cannabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissues
Abstract With the current COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is an urgent…
Open sesame: Identification of sesame oil and oil soot ink in organic deposits of Tang Dynasty lamps from Astana necropolis in China
Abstract Lamp illuminants evidence the exploitation of natural resources, animal and plant domestication, commerce, religious practices and nutrition of ancient…