Bin-Bin Pan

June 20, 2023

Comprehensive pan-cancer analysis identifies FHL2 associated with poor prognosis in lung adenocarcinoma

Abstract Background: The FHL family (four-and-a-half-LIM-only protein family) contains five multifunctional proteins (FHL1-5) that are involved in cell survival, transcriptional…

May 15, 2019

Third BIR domain of XIAP binds to both Cu(II) and Cu(I) in multiple sites and with diverse affinities characterized at atomic resolution

Abstract The X-chromosome linked inhibitor of apoptosis, XIAP, is mainly known as the inhibitor of caspases by direct interaction with…

August 22, 2010

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

Abstract Prolonged exposure to drugs of abuse, such as cannabinoids and opioids, leads to pharmacological tolerance and receptor desensitization in…