Influence of Cannabinoid Receptor 1 Genetic Variants on the Subjective Effects of Smoked Cannabis
Abstract As many jurisdictions consider relaxing cannabis legislation and usage is increasing in North America and other parts of the…
Bernard Le Foll
Cannabis Legalization and Acute Harm From High Potency Cannabis Products: A Narrative Review and Recommendations for Public Health
Abstract Legalization and commercial sale of non-medical cannabis has led to increasing diversity and potency of cannabis products. Some of…
Targeting the Endocannabinoid CB1 Receptor to Treat Body Weight Disorders: A Preclinical and Clinical Review of the Therapeutic Potential of Past and Present CB1 Drugs
Abstract Obesity rates are increasing worldwide and there is a need for novel therapeutic treatment options. The endocannabinoid system has…
Canadian Association of Gastroenterology Position Statement: Use of Cannabis in Gastroenterological and Hepatic Disorders
Keywords: Cannabis, Hepatic disorders, Gastroenterological disorders, Position statement Authors: Christopher N Andrews, Shane M Devlin, Bernard Le Foll, Benedikt Fischer,…
Psychosocial and pharmacological interventions for the treatment of cannabis use disorder
Abstract Cannabis use has been continuously increasing, and cannabis use disorder (CUD) has become a public health issue. Some psychosocial…
Nabiximols combined with motivational enhancement/cognitive behavioral therapy for the treatment of cannabis dependence: A pilot randomized clinical trial
Abstract Background: The current lack of pharmacological treatments for cannabis use disorder (CUD) warrants novel approaches and further investigation of…
Effects of various cannabinoid ligands on choice behaviour in a rat model of gambling
Abstract It is estimated that 0.6–1% of the population in the USA and Canada fulfil the Diagnostic and Statistical Manual…
Prevention of Diet-Induced Obesity Effects on Body Weight and Gut Microbiota in Mice Treated Chronically with Δ9-Tetrahydrocannabinol
Abstract Objective: Acute administration of cannabinoid CB1 receptor agonists, or the ingestion of cannabis, induces short-term hyperphagia. However, the incidence…
Role of the Endogenous Cannabinoid System in Nicotine Addiction: Novel Insights
Abstract Several lines of evidence have shown that the endogenous cannabinoids are implicated in several neuropsychiatric diseases. Notably, preclinical and…