Barkha J. Yadav-Samudrala

June 24, 2024

Cannabinoid receptor 1 positive allosteric modulator ZCZ011 shows differential effects on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice

Abstract The cannabinoid receptor type 1 (CB1R) is a promising therapeutic target for various neurodegenerative diseases, including HIV-1-associated neurocognitive disorder…

May 21, 2024

A helping HAND: therapeutic potential of MAGL inhibition against HIV-1-associated neuroinflammation

Abstract Background: Human immunodeficiency virus (HIV) affects nearly 40 million people globally, with roughly 80% of all people living with…

March 5, 2024

Effects of acute cannabidiol on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice

Abstract Background: Some evidence suggests that cannabidiol (CBD) has potential to help alleviate HIV symptoms due to its antioxidant and…

March 15, 2021

GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration

Abstract Human immunodeficiency virus type 1 (HIV-1) is known to provoke microglial immune responses which likely play a paramount role…