Structural basis for activation of CB1 by an endocannabinoid analog
Abstract Endocannabinoids (eCBs) are endogenous ligands of the cannabinoid receptor 1 (CB1), a G protein-coupled receptor that regulates a number…
Asuka Inoue
Rare, functional, somatic variants in gene families linked to cancer genes: GPCR signaling as a paradigm
Abstract Oncodriver genes are usually identified when mutations recur in multiple tumours. Different drivers often converge in the activation or…