Identification and Validation of JAM-A as a Novel Prognostic and Immune Factor in Human Tumors
Abstract Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R), is a transmembrane glycoprotein that is involved in various…
Aobo Zhang
GJB3: a comprehensive biomarker in pan-cancer prognosis and immunotherapy prediction
Abstract Background: A wide range of connexins are situated between normal-normal cells, cancer-cancer cells, and cancer-normal cells. Abnormalities in connexin…
An association between ATP7B expression and human cancer prognosis and immunotherapy: a pan-cancer perspective
Abstract Background: ATP7B is a copper-transporting protein that contributes to the chemo-resistance of human cancer cells. It remains unclear what…
Systematic pan-cancer analysis of the potential tumor diagnosis and prognosis biomarker P4HA3
Abstract Purpose: Prolyl 4-hydroxylase subunit alpha 3 (P4HA3) is implicated in several cancers’ development. However, P4HA3 has not been reported…
Pan-Cancer Integrated Analysis of HSF2 Expression, Prognostic Value and Potential Implications for Cancer Immunity
Abstract Heat shock factor 2 (HSF2), a transcription factor, plays significant roles in corticogenesis and spermatogenesis by regulating various target…
Pan-Cancer Analysis of the Prognostic and Immunological Role of HSF1: A Potential Target for Survival and Immunotherapy
Abstract Emerging evidence revealed the significant roles of heat shock factor 1 (HSF1) in cancer initiation, development, and progression, but…
Tumor Derived SIGLEC Family Genes May Play Roles in Tumor Genesis, Progression, and Immune Microenvironment Regulation
Abstract Background: SIGLEC family genes can also be expressed on tumor cells in different cancer types, and though it has…
Spectrum of EGFR aberrations and potential clinical implications: insights from integrative pan‐cancer analysis
Abstract Background: Human epidermal growth factor receptor (EGFR) is an oncogenic gene and one of top targets of precision therapy…
Genomewide association study identifies a novel locus for cannabis dependence
Abstract Despite moderate heritability, only one study has identified genomewide significant loci for cannabis-related phenotypes. We conducted meta-analyses of genomewide…