Cuproptosis: molecular mechanisms, cancer prognosis, and therapeutic applications
Abstract Cuproptosis differs from other forms of cell death, such as apoptosis, necroptosis, and ferroptosis, in its unique molecular mechanisms…
Ana Liso Navarro
From bench to bedside: the application of cannabidiol in glioma
Abstract Glioma is the most common malignant tumor in central nervous system, with significant health burdens to patients. Due to…
Pan-cancer analysis of kinesin family members with potential implications in prognosis and immunological role in human cancer
Abstract Background: Kinesin is a molecular motor for transporting “goods” within cells and plays a key role in many types…
Improving Pathways to Care for Patients at High Psychosis Risk in Switzerland: PsyYoung Study Protocol
Abstract Aims: Psychotic disorders are one of the main causes of chronic disability in young people. An at-risk mental state…
Pan-cancer analysis identifies the correlations of Thymosin Beta 10 with predicting prognosis and immunotherapy response
Abstract Introduction: The biological function and prognosis roles of thymosin β(TMSB) 10 are still unclear in pan-cancer. Methods: We retrieved…
Characterization of the functional effects of ferredoxin 1 as a cuproptosis biomarker in cancer
Abstract Background: Cuproptosis is a recently discovered form of programmed cell death. Ferredoxin 1 (FDX1) is a key gene that…
Molecular characterization, clinical relevance and immune feature of m7G regulator genes across 33 cancer types
Abstract Over 170 RNA modifications have been identified after transcriptions, involving in regulation of RNA splicing, processing, translation and decay.…
Pan-cancer analyses of pyroptosis with functional implications for prognosis and immunotherapy in cancer
Abstract Background: Programmed cell death is an active and orderly form of cell death regulated by intracellular genes that plays…
Machine Learning Identifies Pan-Cancer Landscape of Nrf2 Oxidative Stress Response Pathway-Related Genes
Abstract Background: Oxidative stress produced a large amount of reactive oxygen species (ROS), which played a pivotal role in balanced…