Endocannabinoid Signaling Regulates Sleep Stability
Abstract The hypnogenic properties of cannabis have been recognized for centuries, but endogenous cannabinoid (endocannabinoid) regulation of vigilance states is…
Alexandros Makriyannis
Effects of various cannabinoid ligands on choice behaviour in a rat model of gambling
Abstract It is estimated that 0.6–1% of the population in the USA and Canada fulfil the Diagnostic and Statistical Manual…
Role of the Endogenous Cannabinoid System in Nicotine Addiction: Novel Insights
Abstract Several lines of evidence have shown that the endogenous cannabinoids are implicated in several neuropsychiatric diseases. Notably, preclinical and…
Probing the Carboxyester Side Chain in Controlled Deactivation (−)-Δ8-Tetrahydrocannabinols
Abstract We recently reported on a controlled deactivation/detoxification approach for obtaining cannabinoids with improved druggability. Our design incorporates a metabolically…
Expression and Function of Cannabinoid Receptors CB1 and CB2 and Their Cognate Cannabinoid Ligands in Murine Embryonic Stem Cells
Abstract Background: Characterization of intrinsic and extrinsic factors regulating the self-renewal/division and differentiation of stem cells is crucial in determining…