Cannabinoid Regulation of Murine Vaginal Secretion
Abstract Tearing and salivation are wholly dependent on the activity of exocrine (lacrimal and salivary) glands, whereas vaginal moisture and…
Alex Straiker
A Sex-Dependent Cannabinoid CB1 Receptor Role in Circadian Tearing of the Mouse
Abstract Purpose: We have shown that cannabinoid CB1 receptors regulate both salivation and tearing, but for tearing, this regulation is…
Cannabinoid regulation of sex-dependent murine odorant-stimulated salivation
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-77761-4. Article type: Research Article Keywords: Olfactory bulb, Animal…
CB1 Receptor Negative Allosteric Modulators as a Potential Tool to Reverse Cannabinoid Toxicity
Abstract While the opioid crisis has justifiably occupied news headlines, emergency rooms are seeing many thousands of visits for another…
A Critical Evaluation of Terpenoid Signaling at Cannabinoid CB1 Receptors in a Neuronal Model
Abstract In addition to phytocannabinoids, cannabis contains terpenoids that are claimed to have a myriad of effects on the body.…
Cannabinoid CB1 receptors regulate salivation
Abstract Saliva serves multiple important functions within the body that we typically take for granted, such as helping prepare food…
An Evaluation of Understudied Phytocannabinoids and Their Effects in Two Neuronal Models
Abstract Cannabis contains more than 100 phytocannabinoids. Most of these remain poorly characterized, particularly in neurons. We tested a panel…
Cannabinoids Regulate Sensory Processing in Early Olfactory and Visual Neural Circuits
Abstract Our sensory systems such as the olfactory and visual systems are the target of neuromodulatory regulation. This neuromodulation starts…
SGIP1 is involved in regulation of emotionality, mood, and nociception and modulates in vivo signalling of cannabinoid CB1 receptors
Abstract Background and Purpose: Src homology 3‐domain growth factor receptor‐bound 2‐like endophilin interacting protein 1 (SGIP1) interacts with cannabinoid CB1…
THC Regulates Tearing via Cannabinoid CB1 Receptors
Abstract Purpose: Aqueous deficiency dry eye (ADDE) is a chronic condition affecting millions, with symptoms ranging from a dry itchiness…