Alessandra Gemma

September 29, 2025

ABCB1 polymorphisms are associated with clinical response to nabiximols in patients with multiple sclerosis-related spasticity

Keywords: Multiple sclerosis, Single nucleotide polymorphisms, Nabiximols, Spasticity, ABCB1 Authors: Alessandra Gemma, Marco Mauri, Paola Banfi, Maurizio Versino, Alen Zollo,…

February 4, 2023

Effects of Cannabidiol on Innate Immunity: Experimental Evidence and Clinical Relevance

Abstract Cannabidiol (CBD) is the main non-psychotropic cannabinoid derived from cannabis (Cannabis sativa L., fam. Cannabaceae). CBD has received approval…

January 29, 2022

Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition

Abstract Polypharmacology breaks up the classical paradigm of “one-drug, one target, one disease” electing multitarget compounds as potential therapeutic tools…