Clinical value of SPP1 overexpression in patients with papillary thyroid carcinoma
Abstract Background: Secreted phosphoprotein 1 (SPP1) is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. SPP1 is…
Ailin Zhang
Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy
Abstract Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is a cell surface antigen for therapeutic targeting in prostate…
Effect of FOXP2 transcription factor on immune infiltration of thyroid cancer and its potential clinical value
Abstract Background: The clinical outcomes are not always favorable in certain thyroid cancer patients. The effect of Forkhead-box family on…
The expression and significance of efferocytosis and immune checkpoint related molecules in pancancer samples and the correlation of their expression with anticancer drug sensitivity
Abstract Background: The efferocytosis-related molecules have been considered to be correlated with the resistance to cancer chemotherapy. The aim of…
Expression signature, prognosis value, and immune characteristics of Siglec-15 identified by pan-cancer analysis
Abstract Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) is considered a novel anti-tumor target comparable to programmed cell death 1 ligand…
Prognostic lncRNA, miRNA, and mRNA Signatures in Papillary Thyroid Carcinoma
Abstract The current focus in the treatment of papillary thyroid carcinoma (PTC) is tumor progression. The aim of this study…
Upregulation of COL8A1 indicates poor prognosis across human cancer types and promotes the proliferation of gastric cancer cells
Abstract Gastric cancer (GC) was one of the most common types of the digestive system. COL8A1 was reported to be…
Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment
Abstract A growing emphasis in anticancer drug discovery efforts has been on targeting histone acetylation modulators. Here we comprehensively analyze…