Pharmacokinetic and pharmacodynamic properties of cannabigerol in male mice
Abstract Cannabigerol (CBG) is a nonintoxicating phytocannabinoid gaining popularity as a self-medication for anxiety and other conditions; however, its pharmacological…
Aditi Das
Distinct Interactions of Cannabinol and Its Cytochrome P450-Generated Metabolites with Receptors and Sensory Neurons
Abstract Interest in nonpsychotropic cannabinoids like cannabinol (CBN) is increasing for pain therapy. This study delivers critical insights into CBN’s…
Elucidating the Mechanism of Metabolism of Cannabichromene by Human Cytochrome P450s
Abstract Cannabichromene (CBC) is a nonpsychoactive phytocannabinoid well-known for its wide-ranging health advantages. However, there is limited knowledge regarding its…
Mechanistic origin of partial agonism of tetrahydrocannabinol for cannabinoid receptors
Abstract Cannabinoid receptor 1 (CB1) is a therapeutically relevant drug target for controlling pain, obesity, and other central nervous system…