Biobanks, offspring fitness and the influence of developmental plasticity in conservation biology
Abstract Mitigation of the widely known threats to the world’s biodiversity is difficult, despite the strategies and actions proposed by…
Review Article
Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties—a review
Abstract Traditionally, selected plant sources have been explored for medicines to treat convulsions. This continues today, especially in countries with…
Phytocannabinoids: Pharmacological effects, biomedical applications, and worldwide prospection
Abstract Scientific evidence exists about the association between neurological diseases (i.e., Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), multiple…
A Potential Role Exists for Nutritional Interventions in the Chronic Phase of Mild Traumatic Brain Injury, Concussion and Sports-Related Concussion: A Systematic Review
Abstract Mild traumatic brain injury (mTBI) represents a significant burden for individuals, economies, and healthcare systems worldwide. Recovery protocols focus…
Targeting collagen in tumor extracellular matrix as a novel targeted strategy in cancer immunotherapy
Abstract Collagen, the most abundant protein in mammal, is widely expressed in tissues and organs, as well as tumor extracellular…
Lipid-based oral formulation in capsules to improve the delivery of poorly water-soluble drugs
Abstract Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical development, which is linked to their limited oral bioavailability and therapeutic…
Audiogenic epileptic DBA/2 mice strain as a model of genetic reflex seizures and SUDEP
Abstract Epilepsy is a chronic neurological disease characterized by abnormal brain activity, which results in repeated spontaneous seizures. Sudden unexpected…
From Discomfort to Distress: A Critical Analysis of Hyperemesis Gravidarum in the Emergency Room
Abstract Hyperemesis gravidarum (HG) is a severe and debilitating condition characterized by persistent and excessive nausea and vomiting during pregnancy…
Informing the Cannabis Conjecture: From Life’s Beginnings to Mitochondria, Membranes and the Electrome—A Review
Abstract Before the late 1980s, ideas around how the lipophilic phytocannabinoids might be working involved membranes and bioenergetics as these…
Decoding the Postulated Entourage Effect of Medicinal Cannabis: What It Is and What It Isn’t
Abstract The ‘entourage effect’ term was originally coined in a pre-clinical study observing endogenous bio-inactive metabolites potentiating the activity of…