Electrochemical Late-Stage Functionalization
Abstract Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or diversification of novel molecular entities with improved physicochemical…
Review Article
Neuroinflammation in the Central Nervous System: Exploring the Evolving Influence of Endocannabinoid System
Abstract Neuroinflammation is a complex biological process that typically originates as a protective response in the brain. This inflammatory process…
Hexahydrocannabinol Pharmacology, Toxicology, and Analysis: The First Evidence for a Recent New Psychoactive Substance
Abstract Background: During the last two years, hexahydrocannabinol (HHC), the hydrogenated derivative of tetrahydrocannabinol has been freely sold by internet…
Therapeutic Potential of Cannabis: A Comprehensive Review of Current and Future Applications
Abstract Historically, cannabis has been valued for its pain-relieving, anti-inflammatory, and calming properties. Ancient civilizations like the Egyptians, Greeks, and…
Nabiximols is Efficient as Add-On Treatment for Patients with Multiple Sclerosis Spasticity Refractory to Standard Treatment: A Systematic Review and Meta-Analysis of Randomised Clinical Trials
Abstract Background: Spasticity affects 54% of multiple sclerosis (MS) patients at disease onset, but this rate gradually increases with disease…
Brain-Derived Neurotrophic Factor Levels in Cannabis Use Disorders – A Systematic Review and Meta-Analysis
Abstract The prevalence of cannabis use disorders has become a noteworthy global public health issue. Understanding the neurobiological factors associated…
Portable NIR spectroscopy: the route to green analytical chemistry
Abstract There is a growing interest for cost-effective and nondestructive analytical techniques in both research and application fields. The growing…
The roles of FLOT1 in human diseases (Review)
Abstract FLOT1, a scaffold protein of lipid rafts, is involved in several biological processes, including lipid raft protein-dependent or clathrin-independent…
Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets
Abstract Microglia activation is observed in various neurodegenerative diseases. Recent advances in single-cell technologies have revealed that these reactive microglia…
An Observatory for the MET Oncogene: A Guide for Targeted Therapies
Abstract Simple Summary: The MET gene encodes a receptor critical for cell growth and repair. It plays diverse roles in…