Current Challenges and Future Directions in the Assessment of Glucocorticoid Status
Abstract Glucocorticoid (GC) hormones are secreted in a circadian and ultradian rhythm and play a critical role in maintaining physiological…
Review Article
Modulation of neuroinflammation and oxidative stress by targeting GPR55 – new approaches in the treatment of psychiatric disorders
Abstract Pharmacological treatment of psychiatric disorders remains challenging in clinical, pharmacological, and scientific practice. Even if many different substances are…
The Use of Compounds Derived from Cannabis sativa in the Treatment of Epilepsy, Painful Conditions, and Neuropsychiatric and Neurodegenerative Disorders
Abstract Neurological disorders present a wide range of symptoms and challenges in diagnosis and treatment. Cannabis sativa, with its diverse…
Brazilian Psychiatric Association Consensus for the Management of Acute Intoxication: general management and specific interventions for drugs of abuse
Abstract Objectives: To present the Brazilian Psychiatric Association’s Consensus on the Management of Acute Intoxication. Methods: A group of experts…
Phytotherapeutic options for the treatment of epilepsy: pharmacology, targets, and mechanism of action
Abstract Epilepsy is one of the most common, severe, chronic, potentially life-shortening neurological disorders, characterized by a persisting predisposition to…
The use and potential abuse of psychoactive plants in southern Africa: an overview of evidence and future potential
Abstract Background: Most Bantu ethnic groups in southern Africa utilize indigenous herbal medicines, some of which have psychoactive properties. Traditional…
Effectiveness of cannabis use and cannabis use disorder interventions: a European and international data synthesis
Abstract This data synthesis examined the effectiveness of behavioural and pharmacological approaches for cannabis treatment. We integrated findings from high…
Anti-Cancer and Anti-Proliferative Potential of Cannabidiol: A Cellular and Molecular Perspective
Abstract Cannabinoids, the bioactive compounds found in Cannabis sativa, have been used for medicinal purposes for centuries, with early discoveries…
How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges
Abstract Cannabinoids are compounds found in and derived from the Cannabis plants that have become increasingly recognised as significant modulating…
The Relationship between Muscarinic and Cannabinoid Receptors in Neuronal Excitability and Epilepsy: A Review
Abstract Background: Of the seventy million people who suffer from epilepsy, 40 percent of them become resistant to more than…