The Influence of Different Light Spectra on Broiler Chicken Endocrine Systems and Productivity
Abstract Simple Summary: Light plays a crucial role in regulating physiological processes in broiler chickens. It not only helps birds…
Review Article
Dual Role of the Spinal Endocannabinoid System in Response to Noxious Stimuli: Antinociceptive Pathways and Neuropathic Pain Mechanisms
Abstract Neuropathic pain is a clinically challenging syndrome that is largely refractory to conventional therapies. It arises from lesions or…
Cyclodextrin-Based Formulations as a Promising Strategy to Overcome the Blood–Brain Barrier: Historical Overview and Prospects in Glioblastoma Treatment
Abstract Glioblastoma (GB) is one of the most aggressive and treatment-resistant cancers affecting the central nervous system (CNS), predominantly in…
Strategy advancements in placental pharmacokinetics: from in vitro experiments to in silico prediction
Abstract Background: The placental barrier is a critical interface that regulates drug transport between maternal and fetal circulation and is…
A comprehensive review of alkaloids in cancer therapy: focusing on molecular mechanisms and synergistic potential of piperine in colorectal cancer
Abstract Alkaloids exhibit a wide range of anticancer activities, including the induction of apoptosis, regulation of autophagy, arrest of the…
Repurposing Existing Drugs for the Treatment of Post-Traumatic Stress Disorder
Abstract Chronic stress and traumatic events affect the psychological and physiological state of a person. Post-traumatic stress disorder (PTSD) is…
A Systematic Review of Treatment Approaches for Individuals With Coexisting Diabetes and Substance Use Disorder
Abstract Diabetes is a chronic metabolic disease that is widespread and has negative consequences for health and well-being. Substance use…
A comprehensive review of GABA in autism spectrum disorders: associations, mechanisms, and therapeutic implications
Abstract The etiology and pathogenesis of Autism Spectrum Disorder (ASD) are not yet clear. Gamma-aminobutyric acid (GABA), as an inhibitory…
School‐Based Interventions for Reducing Disciplinary School Exclusion. An Updated Systematic Review
Abstract School exclusion—commonly referred to as suspension—is a disciplinary response employed by school authorities to address student misbehaviour. Typically, it…
The potential role of cannabidiol (CBD) in lung cancer therapy: a systematic review of preclinical and clinical evidence
Abstract Background: Lung cancer is one of the most prevalent and lethal cancers worldwide, with limited therapeutic options in advanced…