A Comprehensive Review and Update on Cannabis Hyperemesis Syndrome
Abstract Cannabis, derived from Cannabis sativa plants, is a prevalent illicit substance in the United States, containing over 400 chemicals,…
Review Article
Circular RNAs: novel noncoding players in male infertility
Abstract Infertility is a global problem being associated with emotional and financial burden. Recent studies have shown contribution of a…
Proximal antecedents and acute outcomes of simultaneous alcohol and cannabis use: Systematic review of daily‐ and event‐level studies
Abstract Many studies have revealed that individuals who engage in simultaneous use of alcohol and cannabis report elevated substance‐related consequences…
The Entourage Effect in Cannabis Medicinal Products: A Comprehensive Review
Abstract This study explores the complementary or synergistic effects of medicinal cannabis constituents, particularly terpenes, concerning their therapeutic potential, known…
Enhancing Cannabinoid Bioavailability in Pain Management: The Role of Cyclodextrins
Abstract Chronic pain (CP), including pain related to cancer, affects approximately 2 billion people worldwide, significantly diminishing quality of life…
Cannabis, Endocannabinoids and Brain Development: From Embryogenesis to Adolescence
Abstract The endocannabinoid signalling system (ECS) plays a critical role from the very beginning of embryogenesis. Accordingly, the ECS is…
Harnessing the healing power of nature: a review of natural interventions in substance abuse treatment and prevention
Abstract Background: Substance abuse is a global problem that cuts across all sectors of society and requires innovative solutions that…
Targeting carbohydrate metabolism in colorectal cancer – synergy between DNA-damaging agents, cannabinoids, and intermittent serum starvation
Abstract Chemotherapy is a therapy of choice for many cancers. However, it is often inefficient for long-term patient survival and…
New Insights into the Development of Donepezil-Based Hybrid and Natural Molecules as Multi-Target Drug Agents for Alzheimer’s Disease Treatment
Abstract Alzheimer’s disease (AD) involves a complex pathophysiology with multiple interconnected subpathologies, including protein aggregation, impaired neurotransmission, oxidative stress, and…
Antioxidant Potential of Medicinal Plants in the Treatment of Scabies Infestation
Abstract Oxidative stress, characterized by an overproduction of reactive oxygen species that overwhelm the body’s physiological defense mechanisms, is a…