Cannabinoids and General Anesthetics: Revisiting Molecular Mechanisms of Their Pharmacological Interactions
Abstract Cannabis has been used for recreation and medical purposes for more than a millennium across the world; however, its…
Review Article
Endothelial-to-mesenchymal transition in the tumor microenvironment: Roles of transforming growth factor-β and matrix metalloproteins
Abstract Cancer is a leading cause of global morbidity and mortality. Tumor cells grow in a complex microenvironment, comprising immune…
Cannabinoids for spasticity in patients with multiple sclerosis: A systematic review and meta-analysis
Abstract Background: One of the most disabling symptoms of patients with multiple sclerosis (MS) is spasticity which affects their quality…
Microbial communities and their role in enhancing hemp fiber quality through field retting
Abstract Abstract: The current development of industrial hemp “Cannabis Sativa L.” fibers for technical textiles and industrial applications requires high-quality…
Gibberellic Acid (GA3): A Versatile Chiral Building Block for Syntheses of Pharmaceutical Agents
Abstract Gibberellic acid (GA3), an ent‐kaurene tetracyclic diterpene, has been considered to be a chiral pool for the chemical transformation…
The Potential of Cannabichromene (CBC) as a Therapeutic Agent
Abstract SIGNIFICANCE STATEMENT: Cannabichromene (CBC) has been suggested to have disparate therapeutic benefits such as anti-inflammatory, anticonvulsant, antibacterial, and antinociceptive…
Copper homeostasis and copper-induced cell death in tumor immunity: implications for therapeutic strategies in cancer immunotherapy
Abstract Copper is an important trace element for maintaining key biological functions such as cellular respiration, nerve conduction, and antioxidant…
Optimized guidelines for feminized seed production in high-THC Cannabis cultivars
Abstract With the partial legalization of high-THC Cannabis sativa across 23 states for recreational use and 38 states for medical…
Cannabinoids as Antibacterial Agents: A Systematic and Critical Review of In Vitro Efficacy Against Streptococcus and Staphylococcus
Abstract Background: Two major bacterial pathogens, Staphylococcus aureus and Streptococcus pyogenes, are becoming increasingly antibiotic-resistant. Despite the urgency, only a…
A recent update on the antibacterial effects of distinct bioactive molecules derived from the Cannabis plant
Abstract The number of human infections with multidrug-resistant (MDR) bacteria is increasing worldwide and constitutes a serious threat to human…