Plasma biomarkers in neuropsychiatric syndromes: A narrative review
Abstract Neuropsychiatric symptoms (NPS) are common features of neurodegenerative disease (NDD) but are relatively understudied compared to cognition, especially regarding…
Review Article
The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma
Abstract Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted…
Cannabidiol in pancreatic ductal adenocarcinoma: preclinical evidence, molecular mechanisms, and translational challenges
Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest and most treatment-resistant cancers, with limited progress in improving…
Nanopore sequencing in veterinary medicine: from concepts to clinical applications
Abstract Oxford Nanopore Technologies (ONT) stands at the forefront of third-generation sequencing, utilizing a nanopore sequencing approach to achieve high-throughput…
Environmental behavior and human health risks of PFAS: occurrence, toxicity, and the state-of-the-art removal approaches
Abstract Fluorinated compounds, including poly- and per-fluoroalkyl substances (PFAS), are characterized by complex behavior, environmental persistence, and resistance to degradation.…
P21-activated kinase 4: a potent oncogene, molecular mechanisms and opportunities for targeted therapy
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12935-025-04042-z. Article type: Review Article Keywords: PAK4, Inhibitor, Prognosis,…
Differentiation of Therapeutic and Illicit Drug Use via Metabolite Profiling
Abstract Objectives: The therapeutic use of controlled substances, particularly opioids, stimulants, and benzodiazepines, has significantly increased in recent decades. This…
The role of natural compounds in modulation of small extracellular vesicle biogenesis and lipid metabolism in cancer
Abstract Small extracellular vesicles (sEVs) are vesicles of 15–150 nm in diameter secreted by cells and contain biological compounds that…
Cannabis use patterns, prevalence, and risk factors in Nigeria: a systematic review and meta-analysis
Abstract Background: Reviews on cannabis use have been conducted in high-income countries, but limited data exist in Sub-Saharan Africa. In…
Comprehensive analysis on the implications of IAH1 in cancer development and progression
Abstract Objective: This study aimed to elucidate the role of the IAH1 gene across multiple cancer types. Methods: Using multi-omics…