Recent Developments in the Drug Treatment of Parkinson’s Disease
Abstract Parkinson’s disease (PD) is a common neurodegenerative disorder caused by a spread of misfolded α-synuclein and ascending neuronal degeneration…
Review Article
Cannabidiol in Periodontal Therapy—Is There Hope or Just a Bias? A Systematic Review
Abstract Background: Periodontitis is a chronic inflammatory disease characterized by dysbiotic biofilm formation, progressive destruction of periodontal tissues, and alveolar…
Targeting KITENIN signaling in cancer progression and therapeutic resistance: mechanistic insights and future directions
Abstract KITENIN (KAI1 C-terminal interacting tetraspanin) has emerged as a critical oncogenic mediator involved in tumor initiation, progression, metastasis, and…
Interplay between the HPA axis and inflammation as mechanisms therapeutic targets of Cannabis sativa in depression
Abstract Major Depressive Disorder (MDD) is a highly prevalent and disabling psychiatric disorder, representing a major global health burden across…
Towards Mechanism‐Informed Treatments for Mental Health
Abstract Neuropsychiatric disorders represent a significant global health burden. Despite decades of research, current treatments typically provide only symptomatic relief,…
Adjunctive Cannabidiol for Drug-Resistant Epilepsy: A Systematic Review and Meta-Analysis of Randomized Trials Across Syndromes, Formulations, and Dose Ranges
Abstract Background: Cannabidiol (CBD) has emerged as a promising adjunctive therapy for drug-resistant epilepsy, yet clinical findings remain heterogeneous across…
Industrial and Therapeutic Applications of Hemp: A Review
Abstract Hemp (Cannabis sativa L.) is a multipurpose crop with significant industrial and therapeutic potential. This article reviews the various…
What Do Thirty Years of Neuroimaging Research Tell Us About Recreational Cannabis Use and Brain Integrity? A Narrative Review of the Multimodal Neuroimaging Evidence to Date
Abstract The consumption of cannabinoids is highly prevalent and has been associated with altered structural, functional, and metabolic brain integrity,…
Non-Cisplatin Concurrent Systemic Therapy with Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma: A Network Meta-Analysis of Randomized Clinical Trials
Abstract Head and neck squamous cell carcinoma is one of the most common cancer types worldwide. The standard therapy for…
Mapping the Technological and Pharmacological Landscape of Casearia sylvestris: An Evidence‐Based Prospection for Wound Healing and Pain Management
Abstract Casearia sylvestris Sw. (Salicaceae) is a South American medicinal plant traditionally used for the treatment of inflammatory conditions, pain,…