The Role of the Endocannabinoid System in Human Gametogenesis
Abstract The endocannabinoid system (ECS) is a complex endocrine network involved in maintaining body homeostasis. It comprises endocannabinoids, their receptors…
Review Article
Drugs Used in “Chemsex”/Sexualized Drug Behaviour—Overview of the Related Clinical Psychopharmacological Issues
Abstract Background: “Chemsex” involves the intake of a range of drugs (e.g., synthetic cathinones, gamma-hydroxybutyric acid/gamma-butyrolactone (GHB/GBL), ketamine, methamphetamine, “poppers”,…
Cannabinoids and the Endocannabinoid System in the Treatment of Chronic Rhinosinusitis
Abstract Objective: Recently, the endocannabinoid system (ECS) has emerged as a therapeutic target for various inflammatory diseases, including those of…
Effect of cannabinoids on glutamate levels in the human brain: a systematic review and meta-analysis
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s42238-025-00277-9. Article type: Review Article Keywords: Glutamate, Cannabis, Neuroimaging,…
Cannabis and Dermatological Implications: A Traditional Review of Adverse Cutaneous Reactions and Systemic Risks
Abstract The growing use of cannabis for both recreational and medicinal purposes has raised concerns about its cutaneous adverse effects.…
Endophytes in Cannabis sativa: Identifying and Characterizing Microbes with Beneficial and Detrimental Effects on Plant Health
Abstract The roles of endophytes in Cannabis sativa (cannabis, hemp) remain poorly explored. While in vitro studies suggest that there…
Discriminating evidence – use and misuse of the drug-discrimination test in abuse potential assessment of novel CNS drugs
Abstract Nonclinical testing to predict the abuse potential of central nervous system (CNS) drug candidates is a mandatory part of…
Cannabis Hyperemesis Syndrome in Youth: Clinical Insights and Public Health Implications
Abstract This review focuses on Cannabis Hyperemesis Syndrome (CHS) in youth, a condition linked to chronic cannabis use and characterized…
Cannabinoids: Therapeutic Perspectives for Management of Orofacial Pain, Oral Inflammation and Bone Healing—A Systematic Review
Abstract Cannabinoids, particularly cannabidiol (CBD) and tetrahydrocannabinol (THC), have been increasingly studied for their therapeutic applications in various medical fields.…
Natural small molecules regulating the mitophagy pathway counteract the pathogenesis of diabetes and chronic complications
Abstract Diabetes mellitus (DM) is a chronic metabolic disorder marked by sustained hyperglycemia. These disturbances contribute to extensive damage across…