Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy
Abstract Different physiological and pathological conditions can perturb protein folding in the endoplasmic reticulum, leading to a condition known as…
Review Article
Functional role of cannabinoid receptors in urinary bladder
Abstract Cannabinoids, the active components of Cannabis sativa (maijuana), and their derivatives produce a wide spectrum of central and peripheral…
Advances in diagnostic and treatment options in patients with fibromyalgia syndrome
Abstract Fibromyalgia (FM) is characterized as a chronic, painful, noninflammatory syndrome affecting the musculoskeletal system. In addition to pain, common…
Dynamic regulation of the endocannabinoid system: implications for analgesia
Abstract The analgesic effects of cannabinoids are well documented, but these are often limited by psychoactive side-effects. Recent studies indicate…
From drugs to deprivation: a Bayesian framework for understanding models of psychosis
Abstract Introduction: Various experimental manipulations, usually involving drug administration, have been used to produce symptoms of psychosis in healthy volunteers.…
Cannabis and Breastfeeding
Abstract Cannabis is a drug derived from hemp plant, Cannabis sativa, used both as a recreational drug or as medicine.…
Phenolics: Occurrence and Immunochemical Detection in Environment and Food
Abstract Phenolic compounds may be of natural or anthropogenic origin and be present in the environment as well as in…
Cannabis and Schizophrenia Spectrum Disorders: A Review of Clinical Studies
Abstract Cannabis is the most widely used illegitimate substance in the world, and the number of users has increased by…
Antiaversive Effects of Cannabinoids: Is the Periaqueductal Gray Involved?
Abstract Cannabinoids play an important role in activity-dependent changes in synaptic activity and can interfere in several brain functions, including…
Selective androgen receptor modulators in preclinical and clinical development
Abstract Androgen receptor (AR) plays a critical role in the function of several organs including primary and accessory sexual organs,…