Cannabis and psychosis: Neurobiology
Abstract Cannabis is a known risk factor for schizophrenia, although the exact neurobiological process through which the effects on psychosis…
Review Article
Medical marijuana: A panacea or scourge
Abstract Marijuana (Cannabis sativa) has been used for recreational and medical purposes since ages. Marijuana smoking is an evil, which…
Cannabinoid-hypocretin cross-talk in the central nervous system: what we know so far
Abstract Emerging findings suggest the existence of a cross-talk between hypocretinergic and endocannabinoid systems. Although few studies have examined this…
The Endocannabinoid System and Spermatogenesis
Abstract Spermatogenesis is a complex process in which male germ cells undergo a mitotic phase followed by meiosis and by…
The Endocannabinoid System: A Putative Role in Neurodegenerative Diseases
Abstract Background: Following the characterization of the chemical structure of D9-tetrahydrocannabinol (THC), the main psychoactive constituent of marijuana, researchers have…
The effects of caffeine, nicotine, ethanol, and tetrahydrocannabinol on exercise performance
Abstract Caffeine, nicotine, ethanol and tetrahydrocannabinol (THC) are among the most prevalent and culturally accepted drugs in western society. For…
Cytochrome P450 Family 1 Inhibitors and Structure-Activity Relationships
Abstract With the widespread use of O-alkoxyresorufin dealkylation assays since the 1990s, thousands of inhibitors of cytochrome P450 family 1…
Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE models
Abstract In patients with multiple sclerosis (MS), pain is a frequent and disabling symptom. The prevalence is in the range…
The Endocannabinoid System, Cannabinoids, and Pain
Abstract The endocannabinoid system is involved in a host of homeostatic and physiologic functions, including modulation of pain and inflammation.…
Does Cannabidiol Protect Against Adverse Psychological Effects of THC?
Abstract The recreational use of cannabis can have persistent adverse effects on mental health. Delta-9-tetrahydrocannabinol (THC) is the main psychoactive…