CB2 Cannabinoid Receptor As Potential Target against Alzheimer’s Disease
Abstract The CB2 receptor is one of the components of the endogenous cannabinoid system, a complex network of signaling molecules…
Review Article
Cannabinoid receptor type-1: breaking the dogmas
Abstract The endocannabinoid system (ECS) is abundantly expressed in the brain. This system regulates a plethora of physiological functions and…
Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics
Abstract Chemotherapy-induced nausea and vomiting (CINV) is one of the most common symptoms feared by patients, but may be prevented…
Progress toward pharmacotherapies for cannabis-use disorder: an evidence-based review
Abstract Cannabis is the most widely used and variably regulated drug in the world, with increasing trends of use being…
Study Design and Rationale for the Phase 3 Clinical Development Program of Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials)
Abstract Muscle wasting in cancer is a common and often occult condition that can occur prior to overt signs of…
Modulation of cellular redox homeostasis by the endocannabinoid system
Abstract The endocannabinoid system (ECS) and reactive oxygen species (ROS) constitute two key cellular signalling systems that participate in the…
Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review
Abstract Sleep abnormalities are associated with acute and chronic use of addictive substances. Although sleep complaints associated with use and…
Role of Redox Status in Development of Glioblastoma
Abstract Glioblastoma multiforme (GBM) is a highly aggressive neoplasia, prognosis remains dismal, and current therapy is mostly palliative. There are…
Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview
Abstract The word dementia describes a class of heterogeneous diseases which etiopathogenetic mechanisms are not well understood. There are different…
Neuropharmacology of New Psychoactive Substances (NPS): Focus on the Rewarding and Reinforcing Properties of Cannabimimetics and Amphetamine-Like Stimulants
Abstract New psychoactive substances (NPS) are a heterogeneous and rapidly evolving class of molecules available on the global illicit drug…