The Endocannabinoid System and Oligodendrocytes in Health and Disease
Abstract Cannabinoid-based interventions are being explored for central nervous system (CNS) pathologies such as neurodegeneration, demyelination, epilepsy, stroke, and trauma.…
Review Article
MECHANISMS IN ENDOCRINOLOGY: Anorexia nervosa and endocrinology: a clinical update
Abstract Anorexia nervosa is a syndrome, that is collections of symptoms, which is not defined by its etiology. The severe…
What do Cochrane systematic reviews say about the use of cannabinoids in clinical practice?
Abstract BACKGROUND: The therapeutic effects of cannabinoid compounds have been the center of many investigations. This study provides a synthesis…
Diminished positive affect and traumatic stress: A biobehavioral review and commentary on trauma affective neuroscience
Abstract Post-traumatic stress manifests in disturbed affect and emotion, including exaggerated severity and frequency of negative valence emotions, e.g., fear,…
Animal models of PTSD: a challenge to be met
Abstract Recent years have seen increased interest in psychopathologies related to trauma exposure. Specifically, there has been a growing awareness…
The effect of cannabis exposure on pubertal outcomes: a systematic review
Abstract Purpose: Several countries are legalizing the use of medicinal cannabis and easing restrictions on its recreational use. While adults…
Systems and Synthetic Biology Approaches to Engineer Fungi for Fine Chemical Production
Abstract Since the advent of systems and synthetic biology, many studies have sought to harness microbes as cell factories through…
New Perspectives on the Use of Cannabis in the Treatment of Psychiatric Disorders
Abstract Following the discovery of the endocannabinoid system and its potential as a therapeutic target for various pathological conditions, growing…
Marijuana Use and Hypothalamic-Pituitary-Adrenal Axis Functioning in Humans
Abstract Preclinical studies suggest cannabinoids affect functioning of the hypothalamic-pituitary-adrenal (HPA) axis, but little is known about the effects of…
Endocannabinoids and related N-acylethanolamines: biological activities and metabolism
Abstract The plant Cannabis sativa contains cannabinoids represented by Δ9-tetrahydrocannabinol, which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2…