Herbal Preparations of Medical Cannabis: A Vademecum for Prescribing Doctors
Abstract Cannabis has been used for centuries for therapeutic purposes. In the last century, the plant was demonized due to…
Review Article
Unraveling the Intoxicating and Therapeutic Effects of Cannabis Ingredients on Psychosis and Cognition
Abstract Research evidence suggests a dose–response relationship for the association between cannabis use and risk of psychosis. Such relationship seems…
Irritability in Huntington’s Disease
Abstract Huntington’s disease (HD) is a heritable and fatal neurodegenerative disease characterized by a triad of motor, cognitive and neuropsychiatric…
Advances in Neurobiology and Pharmacology of GPR12
Abstract GPR12 is a G protein-coupled orphan receptor genetically related to type 1 and type 2 cannabinoid receptors (CB1 and…
Cannabinomics: Application of Metabolomics in Cannabis (Cannabis sativa L.) Research and Development
Abstract Cannabis (Cannabis sativa L.) is a complex, polymorphic plant species, which produces a vast array of bioactive metabolites, the…
Understanding polygenic models, their development and the potential application of polygenic scores in healthcare
Abstract The use of genomic information to better understand and prevent common complex diseases has been an ongoing goal of…
The Impact of Transcription Factor Prospero Homeobox 1 on the Regulation of Thyroid Cancer Malignancy
Abstract Transcription factor Prospero homeobox 1 (PROX1) is continuously expressed in the lymphatic endothelial cells, playing an essential role in…
A Balanced Approach for Cannabidiol Use in Chronic Pain
Abstract Cannabidiol (CBD), the major non-psychoactive constituent of Cannabis sativa L., has gained traction as a potential treatment for intractable…
Endocannabinoid System Components as Potential Biomarkers in Psychiatry
Abstract The high heterogeneity of psychiatric disorders leads to a lack of diagnostic precision. Therefore, the search of biomarkers is…
Cannabidiol and Other Non-Psychoactive Cannabinoids for Prevention and Treatment of Gastrointestinal Disorders: Useful Nutraceuticals?
Abstract Cannabis sativa is an aromatic annual flowering plant with several botanical varieties, used for different purposes, like the production…