Advances in Management of Neuropsychiatric Syndromes in Neurodegenerative Diseases
Abstract Purpose of Review: Neuropsychiatric syndromes (NPS) are common in neurodegenerative disorders (NDD). This review describes the role of NPS…
Review Article
Distribution of cannabinoid synthase genes in non-Cannabis organisms
Abstract Electronic supplementary material: The online version of this article (10.1186/s42238-019-0008-7) contains supplementary material, which is available to authorized users.…
Opportunities for cannabis in supportive care in cancer
Abstract Cannabis has the potential to modulate some of the most common and debilitating symptoms of cancer and its treatments,…
The Potential of Cannabidiol as a Treatment for Psychosis and Addiction: Who Benefits Most? A Systematic Review
Abstract The endogenous cannabinoid (eCB) system plays an important role in the pathophysiology of both psychotic disorders and substance use…
A systematic review of cannabidiol dosing in clinical populations
Abstract Aims: Cannabidiol (CBD) is a cannabis‐derived medicinal product with potential application in a wide‐variety of contexts; however, its effective…
Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms
Abstract Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that…
Impacts of cannabinoid epigenetics on human development: reflections on Murphy et. al. ‘cannabinoid exposure and altered DNA methylation in rat and human sperm’ epigenetics 2018; 13: 1208-1221.
Abstract Recent data from the Kollins lab (‘Cannabinoid exposure and altered DNA methylation in rat and human sperm’ Epigenetics 2018;…
Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use
Abstract Cannabidiol (CBD) is ubiquitous in state-based medical cannabis programs and consumer products for complementary health or recreational use. CBD…
A General Introduction to Glucocorticoid Biology
Abstract Glucocorticoids (GCs) are steroid hormones widely used for the treatment of inflammation, autoimmune diseases, and cancer. To exert their…
From Cannabinoids and Neurosteroids to Statins and the Ketogenic Diet: New Therapeutic Avenues in Rett Syndrome?
Abstract Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused mainly by mutations in the MECP2 gene, being one of…