Abuse of Licit and Illicit Psychoactive Substances in the Workplace: Medical, Toxicological, and Forensic Aspects
Abstract About one-third of adult life is spent in the workplace. The use of psychoactive substances is a major preventable…
Review Article
From Cannabis sativa to Cannabidiol: Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases
Abstract Cannabis sativa, commonly known as marijuana, contains a pool of secondary plant metabolites with therapeutic effects. Besides Δ9-tetrahydrocannabinol that…
Involvement of Metabolic Lipid Mediators in the Regulation of Apoptosis
Abstract Apoptosis is the physiological mechanism of cell death and can be modulated by endogenous and exogenous factors, including stress…
Management of Cancer Cachexia: Attempting to Develop New Pharmacological Agents for New Effective Therapeutic Options
Abstract Cancer cachexia (CC) is a multifactorial syndrome characterized by systemic inflammation, uncontrolled weight loss and dramatic metabolic alterations. This…
Phytocannabinoids: Useful Drugs for the Treatment of Obesity? Special Focus on Cannabidiol
Abstract Currently, an increasing number of diseases related to insulin resistance and obesity is an alarming problem worldwide. It is…
Pentameric Ligand-Gated Ion Channels as Pharmacological Targets Against Chronic Pain
Abstract Chronic pain is a common detrimental condition that affects around 20% of the world population. The current drugs to…
Cannabis Microbiome and the Role of Endophytes in Modulating the Production of Secondary Metabolites: An Overview
Abstract Plants, including cannabis (Cannabis sativa subsp. sativa), host distinct beneficial microbial communities on and inside their tissues and organs,…
Dosage, Efficacy and Safety of Cannabidiol Administration in Adults: A Systematic Review of Human Trials
Abstract Considering data from in vitro and in vivo studies, cannabidiol (CBD) seems to be a promising candidate for the…
A Review of Cases of Marijuana and Violence
Abstract Marijuana is the most consumed illicit drug in the world, with over 192 million users. Due to the current…
Immune Responses Regulated by Cannabidiol
Abstract Introduction: Cannabidiol (CBD) as Epidiolex® (GW Pharmaceuticals) was recently approved by the U.S. Food and Drug Administration (FDA) to…