Adverse effects of heavy cannabis use: even plants can harm the brain
Authors: Lucia Sideli, Giulia Trotta, Edoardo Spinazzola, Caterina La Cascia, Marta Di Forti Affiliations: Department of Psychosis Studies, Institute of…
Review Article
Terpenoids as Potential Geroprotectors
Abstract Terpenes and terpenoids are the largest groups of plant secondary metabolites. However, unlike polyphenols, they are rarely associated with…
Advances in the discovery of exosome inhibitors in cancer
Abstract Exosomes are small membrane vesicles released by most eukaryotic cells. They are considered to play an essential role in…
One Is Not Enough: Understanding and Modeling Polysubstance Use
Abstract Substance use disorder (SUD) is a chronic, relapsing disease with a highly multifaceted pathology that includes (but is not…
A systematic review of the effectiveness of employer‐led interventions for drug misuse
Abstract Aims: Employers in the United States incur substantial costs associated with substance use disorders. Our goal was to examine…
Can Physical Activity Support the Endocannabinoid System in the Preventive and Therapeutic Approach to Neurological Disorders?
Abstract The worldwide prevalence of neurological and neurodegenerative disorders, such as depression or Alzheimer’s disease, has spread extensively throughout the…
Protein Interactors and Trafficking Pathways That Regulate the Cannabinoid Type 1 Receptor (CB1R)
Abstract The endocannabinoid system (ECS) acts as a negative feedback mechanism to suppress synaptic transmission and plays a major role…
Context matters: the psychoneurobiological determinants of placebo, nocebo and context-related effects in physiotherapy
Abstract Background: Placebo and nocebo effects embody psychoneurobiological phenomena where behavioural, neurophysiological, perceptive and cognitive changes occur during the therapeutic…
Neuroprotection or Neurotoxicity of Illicit Drugs on Parkinson’s Disease
Abstract Parkinson’s Disease (PD) is currently the most rapid growing neurodegenerative disease and over the past generation, its global burden…
Medical cannabis in the UK: From principle to practice
Abstract Background: In the UK, medical cannabis was approved in November 2018, leading many patients to believe that the medicine…