Cannabis based medicines and cannabis dependence: A critical review of issues and evidence
Abstract Cannabis has been legalised for medical use in an ever-increasing number of countries. A growing body of scientific evidence…
Review Article
Opportunities, Challenges and Pitfalls of Using Cannabidiol as an Adjuvant Drug in COVID-19 †
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may lead to coronavirus disease 2019 (COVID-19) which, in turn, may…
When Cannabis Use Goes Wrong: Mental Health Side Effects of Cannabis Use That Present to Emergency Services
Abstract Cannabis use is a modifiable risk factor for the development and exacerbation of mental illness. The strongest evidence of…
Discovering the Lost Reward: Critical Locations for Endocannabinoid Modulation of the Cortico–Striatal Loop That Are Implicated in Major Depression
Abstract Depression, the most prevalent psychiatric disorder in the Western world, is characterized by increased negative affect (i.e., depressed mood,…
Cannabidiol as a Potential Treatment for Anxiety and Mood Disorders: Molecular Targets and Epigenetic Insights from Preclinical Research
Abstract Cannabidiol (CBD) is the most abundant non-psychoactive component of cannabis; it displays a very low affinity for cannabinoid receptors,…
The Immunopathology of COVID-19 and the Cannabis Paradigm
Abstract Coronavirus disease-19 caused by the novel RNA betacoronavirus SARS-CoV2 has first emerged in Wuhan, China in December 2019, and…
Cannabinoids in Audiogenic Seizures: From Neuronal Networks to Future Perspectives for Epilepsy Treatment
Abstract Cannabinoids and Cannabis-derived compounds have been receiving especial attention in the epilepsy research scenario. Pharmacological modulation of endocannabinoid system’s…
From an Alternative Medicine to a New Treatment for Refractory Epilepsies: Can Cannabidiol Follow the Same Path to Treat Neuropsychiatric Disorders?
Abstract Although cannabis has been known for ages as an “alternative medicine” to provide relief from seizures, pain, anxiety, and…
The emergency department care of the cannabis and synthetic cannabinoid patient: a narrative review
Abstract Background: Cannabis is the most prevalent illegal drug used and the second most common cause of ED drug-related complaints…
Cannabidiol in the Treatment of Epilepsy
Abstract Anecdotal reports addressing the successful seizure treatment of severe epilepsies with cannabidiol (CBD) have increased both public interest and…