Molecular Pharmacology of Synthetic Cannabinoids: Delineating CB1 Receptor-Mediated Cell Signaling
Abstract Synthetic cannabinoids (SCs) are a class of new psychoactive substances (NPSs) that exhibit high affinity binding to the cannabinoid…
Review Article
Integrating fish models in tuberculosis vaccine development
Abstract Tuberculosis is a chronic infection by Mycobacterium tuberculosis that results in over 1.5 million deaths worldwide each year. Currently,…
Roles of Cannabinoids in Melanoma: Evidence from In Vivo Studies
Abstract Melanoma is the fourth most common type of cancer diagnosed in Australians after breast, prostate, and colorectal cancers. While…
Pain in NMOSD and MOGAD: A Systematic Literature Review of Pathophysiology, Symptoms, and Current Treatment Strategies
Abstract Neuromyelitis optica spectrum disorders (NMOSDs) and myelin oligodendrocyte glycoprotein-antibody-associated disease (MOGAD) are autoimmune inflammatory disorders of the central nervous…
Cannabinoids for People with ASD: A Systematic Review of Published and Ongoing Studies
Abstract The etiopathogenesis of autism spectrum disorder (ASD) remains largely unclear. Among other biological hypotheses, researchers have evidenced an imbalance…
Current Aspects of the Endocannabinoid System and Targeted THC and CBD Phytocannabinoids as Potential Therapeutics for Parkinson’s and Alzheimer’s Diseases: a Review
Abstract Neurodegeneration leading to Parkinson’s disease (PD) and Alzheimer’s disease (AD) has become a major health burden globally. Current treatments…
Cannabidiol as a Novel Therapeutic for Immune Modulation
Abstract The immune-suppressive effects of cannabidiol (CBD) are attributed to the modulation of essential immunological signaling pathways and receptors. Mechanistic…
So near yet so far: why won’t the UK prescribe medical cannabis?
Abstract Although cannabis-based products for medicinal use are now legal in the UK, it is still challenging for patients to…
Bibenzyls and bisbybenzyls of bryophytic origin as promising source of novel therapeutics: pharmacology, synthesis and structure-activity
Abstract Background: The amphibian, non-vascular, gametophyte-dominant, bio-indicator class, bryophytes; with their wide ranges of habitat have attained importance due to…
Management strategies for the treatment and prevention of postoperative/postdischarge nausea and vomiting: an updated review
Abstract Postoperative nausea and vomiting (PONV) and postdischarge nausea and vomiting (PDNV) remain common and distressing complications following surgery. The…