Cannabidiol and the Canonical WNT/β-Catenin Pathway in Glaucoma
Abstract Glaucoma is a progressive neurodegenerative disease which constitutes the main frequent cause of irreversible blindness. Recent findings have shown…
Review Article
The Clinical Value of Nutritional Care before and during Active Cancer Treatment
Abstract Malnutrition and muscle wasting are frequently reported in cancer patients, either linked to the tumor itself or caused by…
Molecular Mechanism of Cannabinoids in Cancer Progression
Abstract Cannabinoids are a family of heterogeneous compounds that mostly interact with receptors eliciting several physiological effects both in the…
Functional Fine-Tuning of Metabolic Pathways by the Endocannabinoid System—Implications for Health and Disease
Abstract The endocannabinoid system (ECS) employs a huge network of molecules (receptors, ligands, and enzymatic machinery molecules) whose interactions with…
Phytocannabinoids: General Aspects and Pharmacological Potential in Neurodegenerative Diseases
Abstract In the last few years research into Cannabis and its constituent phytocannabinoids has burgeoned, particularly in the potential application…
Chronic Pain in Dogs and Cats: Is There Place for Dietary Intervention with Micro-Palmitoylethanolamide?
Abstract Simple Summary: Chronic pain is being increasingly recognized and addressed in small animal practice. The recent recognition that inability…
Fermentation Strategies for Production of Pharmaceutical Terpenoids in Engineered Yeast
Abstract Terpenoids, also known as isoprenoids, are a broad and diverse class of plant natural products with significant industrial and…
Topical Treatments and Their Molecular/Cellular Mechanisms in Patients with Peripheral Neuropathic Pain—Narrative Review
Abstract Neuropathic pain in humans results from an injury or disease of the somatosensory nervous system at the peripheral or…
Endocannabinoid System Dysregulation from Acetaminophen Use May Lead to Autism Spectrum Disorder: Could Cannabinoid Treatment Be Efficacious?
Abstract Persistent deficits in social communication and interaction, and restricted, repetitive patterns of behavior, interests or activities, are the core…
New paradigms for the treatment of lysosomal storage diseases: targeting the endocannabinoid system as a therapeutic strategy
Abstract Over the past three decades the lysosomal storage diseases have served as model for rare disease treatment development. While…