Cannabinoids and Inflammations of the Gut-Lung-Skin Barrier
Abstract Recent studies have identified great similarities and interferences between the epithelial layers of the digestive tract, the airways and…
Review Article
Pro-Inflammatory Cytokines: Potential Links between the Endocannabinoid System and the Kynurenine Pathway in Depression
Abstract Substance use/abuse is one of the main causes of depressive symptoms. Cannabis and synthetic cannabinoids in particular gained significant…
Cannabinoids and Terpenes: How Production of Photo-Protectants Can Be Manipulated to Enhance Cannabis sativa L. Phytochemistry
Abstract Cannabis sativa L. is cultivated for its secondary metabolites, of which the cannabinoids have documented health benefits and growing…
The endocannabinoid system, cannabis, and cannabidiol: Implications in urology and men’s health
Abstract Background: The endocannabinoid system is a neuromodulatory system responsible for partial regulation of cognitive and emotional processes in the…
Mechanisms of Nausea and Vomiting: Current Knowledge and Recent Advances in Intracellular Emetic Signaling Systems
Abstract Nausea and vomiting are common gastrointestinal complaints that can be triggered by diverse emetic stimuli through central and/or peripheral…
Suicidality and Cannabidiol: Opportunities and Challenges
Abstract Cannabidiol (CBD) is gaining considerable attention in the research community with promising results in a variety of neuropsychiatric conditions.…
Advances and Perspectives in Tissue Culture and Genetic Engineering of Cannabis
Abstract For a long time, Cannabis sativa has been used for therapeutic and industrial purposes. Due to its increasing demand…
Cannabidiol and Sodium Channel Pharmacology: General Overview, Mechanism, and Clinical Implications
Abstract Voltage-gated sodium (Nav) channels initiate action potentials in excitable tissues. Altering these channels’ function can lead to many pathophysiological…
Mediterranean Diet and Neurodegenerative Diseases: The Neglected Role of Nutrition in the Modulation of the Endocannabinoid System
Abstract Neurodegenerative disorders are a widespread cause of morbidity and mortality worldwide, characterized by neuroinflammation, oxidative stress and neuronal depletion.…
The Endocannabinoid System as a Therapeutic Target in Diabetic Peripheral Neuropathic Pain: A Review
Abstract Diabetic peripheral neuropathy (DPN) is characterized by progressive loss of peripheral nerves, which causes numbness, weakness, and severe pain.…