Cognitive Impairment and Dementia: Gaining Insight through Circadian Clock Gene Pathways
Abstract Neurodegenerative disorders affect fifteen percent of the world’s population and pose a significant financial burden to all nations. Cognitive…
Review Article
Epigenetic Regulation of Cannabinoid-Mediated Attenuation of Inflammation and Its Impact on the Use of Cannabinoids to Treat Autoimmune Diseases
Abstract Chronic inflammation is considered to be a silent killer because it is the underlying cause of a wide range…
Cannabinoid Receptor 1 Inhibition in Chronic Kidney Disease: A New Therapeutic Toolbox
Abstract Chronic kidney disease (CKD) concerns millions of individuals worldwide, with few therapeutic strategies available to date. Recent evidence suggests…
Glucocorticoids, Stress and Delta-9 Tetrahydrocannabinol (THC) during Early Embryonic Development
Abstract Elevated molecular stress in women is known to have negative impacts on the reproductive development of oocytes and the…
An Autonomous Cannabinoid System in Islets of Langerhans
Abstract While endocannabinoids (ECs) and cannabis were primarily studied for their nervous system effects, it is now clear that ECs…
Cannabinoquinones: Synthesis and Biological Profile
Abstract Neutral cannabinoids are oxidatively unstable and are converted into quinone derivatives by atmospheric- and/or chemical oxidative dearomatization. The study…
From the Clinic to the Laboratory, and Back Again: Investigations on Cannabinoids and Endocannabinoid System Modulators for Treating Schizophrenia
Abstract The present mini-review focuses on animal models of schizophrenia that have explored the effects of cannabidiol (CBD; a non-psychoactive…
Potential impacts of soil microbiota manipulation on secondary metabolites production in cannabis
Abstract Background: Cannabis growing practices and particularly indoor cultivation conditions have a great influence on the production of cannabinoids. Plant-associated…
The Role of Organic Small Molecules in Pain Management
Abstract In this review, a timeline starting at the willow bark and ending in the latest discoveries of analgesic and…
Effects of illicit drugs on structural and functional impairment of testis, endocrinal disorders, and molecular alterations of the semen
Abstract Illicit drug use is growing among young people, which is one of the major problems in today’s society that…