Cannabidiol (CBD) as a novel treatment in the early phases of psychosis
Abstract The pharmacological interventions available for individuals in the early stages of psychosis are extremely limited. For those at clinical…
Review Article
Early Consumption of Cannabinoids: From Adult Neurogenesis to Behavior
Abstract The endocannabinoid system (ECS) is a crucial modulatory system in which interest has been increasing, particularly regarding the regulation…
Consideration of sex as a biological variable in the translation of pharmacotherapy for stress-associated drug seeking
Abstract Stress is a frequent precipitant of relapse to drug use. Pharmacotherapies targeting a diverse array of neural systems have…
Cognitive Impairment and Dementia: Gaining Insight through Circadian Clock Gene Pathways
Abstract Neurodegenerative disorders affect fifteen percent of the world’s population and pose a significant financial burden to all nations. Cognitive…
Cannabinoid Receptor 1 Inhibition in Chronic Kidney Disease: A New Therapeutic Toolbox
Abstract Chronic kidney disease (CKD) concerns millions of individuals worldwide, with few therapeutic strategies available to date. Recent evidence suggests…
Glucocorticoids, Stress and Delta-9 Tetrahydrocannabinol (THC) during Early Embryonic Development
Abstract Elevated molecular stress in women is known to have negative impacts on the reproductive development of oocytes and the…
Epigenetic Regulation of Cannabinoid-Mediated Attenuation of Inflammation and Its Impact on the Use of Cannabinoids to Treat Autoimmune Diseases
Abstract Chronic inflammation is considered to be a silent killer because it is the underlying cause of a wide range…
From the Clinic to the Laboratory, and Back Again: Investigations on Cannabinoids and Endocannabinoid System Modulators for Treating Schizophrenia
Abstract The present mini-review focuses on animal models of schizophrenia that have explored the effects of cannabidiol (CBD; a non-psychoactive…
An Autonomous Cannabinoid System in Islets of Langerhans
Abstract While endocannabinoids (ECs) and cannabis were primarily studied for their nervous system effects, it is now clear that ECs…
Cannabinoquinones: Synthesis and Biological Profile
Abstract Neutral cannabinoids are oxidatively unstable and are converted into quinone derivatives by atmospheric- and/or chemical oxidative dearomatization. The study…