Enhancing Endocannabinoid Control of Stress with Cannabidiol
Abstract The stress response is a well-defined physiological function activated frequently by life events. However, sometimes the stress response can…
Review Article
Role of Phytoconstituents as PPAR Agonists: Implications for Neurodegenerative Disorders
Abstract Peroxisome proliferator-activated receptors (PPAR-γ, PPAR-α, and PPAR-β/δ) are ligand-dependent nuclear receptors that play a critical role in the regulation…
Nuclear RNA Exosome and Pervasive Transcription: Dual Sculptors of Genome Function
Abstract The genome is pervasively transcribed across various species, yielding numerous non-coding RNAs. As a counterbalance for pervasive transcription, various…
RKIP Pleiotropic Activities in Cancer and Inflammatory Diseases: Role in Immunity
Abstract Simple Summary: The human body consists of tissues and organs formed by cells. In each cell there is a…
Cladribine as a Potential Object of Nucleoside Transporter-Based Drug Interactions
Abstract Cladribine is a nucleoside analog that is phosphorylated in its target cells (B and T-lymphocytes) to its active triphosphate…
Medical cannabinoids for treatment of neuropsychiatric symptoms in dementia: a systematic review
Abstract Introduction: Neuropsychiatric symptoms are an integral component of the natural history of dementia, occurring from prodromal to advanced stages…
New Insights in the Involvement of the Endocannabinoid System and Natural Cannabinoids in Nicotine Dependence
Abstract Nicotine, the main psychoactive component in tobacco smoke, plays a major role in tobacco addiction, producing a high morbidity…
Designing Natural Polymer-Based Capsules and Spheres for Biomedical Applications—A Review
Abstract Natural polymers, such as polysaccharides and polypeptides, are potential candidates to serve as carriers of biomedical cargo. Natural polymer-based…
Cannabinoid interventions for improving cachexia outcomes in cancer: a systematic review and meta‐analysis
Abstract Cancer‐associated cachexia (CAC) is a wasting syndrome characterized by involuntary weight loss and anorexia. Clear definition and diagnostic criteria…
The Endocannabinoid System in Glial Cells and Their Profitable Interactions to Treat Epilepsy: Evidence from Animal Models
Abstract Epilepsy is one of the most common neurological conditions. Yearly, five million people are diagnosed with epileptic-related disorders. The…